Hydrolyzed protein accelerates the gastro-intestinal transport of formula in preterm infants

Creators: Mihatsch, Walter and Högel, Josef and Pohlandt, Frank
Title: Hydrolyzed protein accelerates the gastro-intestinal transport of formula in preterm infants
Item Type: Article or issue of a publication series
Journal or Series Title: Acta Paediatrica : nurturing the child
Page Range: pp. 196-198
Date: February 2001
Divisions: Gesundheitsmanagement
Abstract: Vomiting, large gastric residuals and abdominal distension are common in very immature infants on formula feeding. The present trial investigated whether a protein hydrolysate formula reduces the gastrointestinal transit time in preterm infants. Fifteen preterm infants (median gestational age 29 (24-32) wk, birthweight 1241 (660-1900) g, postnatal age 18 (5-54) d) on full enteral feeds (>150 ml/kg*d) were enrolled. It was hypothesized that the gastrointestinal transit time is at least 2 h shorter when protein hydrolysate formula is fed compared with standard preterm formula. In a randomized cross-over design study, each formula was fed for 5 d. On days 4 and 9 the gastrointestinal transit time was estimated using carmine red. The protein hydrolysate formula had a markedly shorter gastrointestinal transit time (9.8 h) than the standard formula (19 h) (p = 0.0022, two-sided Mann-Whitney U test). Conclusion: The hydrolysate protein formula accelerated gastrointestinal transit of milk and stools, but whether hydrolysate formulas enable a more rapid establishment of full enteral feeding in preterm infants needs to be investigated.
Forthcoming: No
Citation:

Mihatsch, Walter and Högel, Josef and Pohlandt, Frank (2001) Hydrolyzed protein accelerates the gastro-intestinal transport of formula in preterm infants. Acta Paediatrica : nurturing the child, 90 (2). pp. 196-198. ISSN 1651-2227

Actions for admins (login required)

View Item in edit mode View Item in edit mode